Blood Cancer Treatment in Israel
Head of the Department of Hematology
Head of the Department of Hematology
In 34% of patients who come to Israel from Eastern Europe to treat blood cancer, Israeli hematologists-oncologists do not confirm cancer.
Testing for blood cancer in Ichilov takes 3-4 days and costs $2,932.
Hematopoietic stem cell transplantation: non-myeloablative stem cell transplantation, mini-transplant.
Advanced chemotherapy drugs: nelarabine (Arranon).
Targeted therapy drugs: enasidenib (Idhifa), venetoclax (Venclexta), midostaurin (Rydapt), gilteritinib (Xospata), pevonedistat, uproleselan, imatinib (Gleevec), nilotinib (Tasigna), dasatinib (Sprycel), ponatinib (Iclusig), duvelisib, tenalisib, buparlisib, ruxolitinib, crizotinib.
Immunotherapy: CAR T-cell therapy, drugs blinatumomab (Blincyto), inotuzumabozogamicin (Besponsa), brentuximab vedotin (Adcetris), moxetumomabpasudotox. Lymphoma vaccines.
Blood cancer diagnosis and treatment in Top Ichilov is provided by a multidisciplinary team including:
- Hematologist-oncologist, Doctor F. Aviv;
- Radiation oncologist, Doctor T. Rabin;
- Nuclear medicine specialist, Professor E. Even-Sapir.
WHAT TO EXPECT FROM BLOOD CANCER DIAGNOSIS IN TOP ICHILOV
First Day: Initial Consultation
The patient visits a specialist physician from the Department of Diagnostics. She conducts a physical exam, takes health history, and refers the patient for laboratory and instrumental examinations. If the patient has bone marrow biopsy materials, they are sent for revision. Revision results will be ready in 6-10 days.
Second Day: Examination
In the morning, the patient undergoes laboratory blood testing. Then, PET-CT is done. This is an instrumental examination which helps determine the stage and spread of cancer. All procedures and consultations are organized by a medical coordinator who also provides Hebrew translation.
Third Day: Specialist Consultations and Treatment Planning.
The patient receives examination results and consults a hematologist-oncologist – Prof. E. Naparstek or Dr. O. Gur – to plan treatment in Israel. Price for blood cancer diagnosis: $2,932. Duration of examination: 3-4 days.
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PHYSICIANS SPECIALIZING IN BLOOD CANCER IN TOP ICHILOV
Treatment and diagnosis of blood cancer patients in Top Ichilov is provided by the leading Israeli oncologists:
Professor Ella Naparstek, leading hematologist-oncologist, specialist in blood cancer treatment. Professional experience: over 40 years. Has been Head of the Ichilov Hospital Hematology Department for 16 years. Provides treatment for blood cancers in accordance with international protocols.
Doctor Odelia Gur, Head of the Ichilov Hospital Outpatient Hematology Unit. Professional experience: over 30 years. Speaks 3 languages (Hebrew, English, Russian). Uses advanced protocols for blood cancer treatment. One of the best Israeli physicians according to the “Forbes” magazine.
Doctor Irina Stefanski, oncologist, Head of Chemotherapy Department, Deputy Head of Oncology Department. Professional experience: about 27 years. One of the most experienced and reputable medical oncologists in Israel.
4 EFFECTIVE BLOOD CANCER TREATMENT METHODS IN ISRAEL
After precise diagnosis, the Israeli physician develops a personalized treatment program. In total, there are 4 most effective blood cancer treatment methods:
- Radiotherapy (radiation therapy);
- Targeted therapy.
Chemotherapy is a common treatment method for blood cancer. From the start, chemotherapy drugs destroy tumor cells. At this stage, doctors may order stem cell transplantation to gradually replace hematopoietic stem cells destroyed by powerful chemotherapy drugs. In Israel, stem cells may be taken both from the patient themselves and from non-related or relative donor. Chemotherapy may be either systemic (affecting the whole body) or directed at certain body parts containing cancer cells. For instance, blood cancer is an indication for intrathecal administration of chemotherapy drugs into the spinal canal. The personalized approach to planning chemotherapy for leukemia helps minimize the side effects of this treatment.
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Sometimes, radiotherapy (radiation therapy) is recommended for blood cancer. The radiation is directed either at certain organs affected by tumor cells or at the whole body.
This group of drugs includes interferon. The goal of biological therapy is to stimulate the immune system and help it destroy cancer cells.
Patients with acute myeloid leukemia have tyrosine kinase, an enzyme that promotes growth and division of malignant cells. Gilteritinib is a new biological drug able to block tyrosine kinase and thus, stop the progression of the disease. Acute myeloid leukemia may be also treated with other drugs, including ivosidenib. This medication blocks the IDH gene since its mutation prevents blood cell maturation. This very mutation can cause acute myeloid leukemia. The drug helps overcome the disease.
Targeted drugs are able to “recognize” tumor cells and destroy them while healthy cells remain unaffected.
BLOOD CANCER TREATMENT METHODS IMPLEMENTED IN 2022
- CAR T-cell therapy (adoptive cell therapy with genetically engineered T-lymphocytes). This advanced immunotherapy method is used for some types of leukemia and non-Hodgkin lymphoma. During treatment, T-cells are removed from the patient. These are the lymphocytes that fight foreign cells, including cancer cells. T-lymphocytes are modified in the laboratory, multiplied and administered back into the patient’s body.
- Targeted drug inotuzumab ozogamicin (Besponsa). This is anti-CD22 monoclonal antibody combined with a chemotherapy drug. The CD22 protein is found on the surface of some leukemia cells. The antibody acts like a homing system and directs the chemotherapy drug into malignant cells. Besponsa is used for some types of acute lymphoblastic leukemia. Clinical trials show that the use of this medication increases survival in comparison with traditional therapy.
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How to Receive Blood Cancer Treatment in Top Ichilov
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Дата публикации July 25th, 2022