Parkinson’s disease is a neurological disorder affecting the brain cells that control movement. The symptoms of the disorder include shaking, stiffness, and balance problems as well as depression and dementia. Some patients experience problems with the autonomic nervous system, a part of the nervous system that helps control blood pressure and the functions of the colon and the bladder.
In Israel, at Top Ichilov Clinic, Parkinson’s disease patients are offered cutting-edge treatment methods including effective medication therapy regimens and deep brain stimulation.
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At Top Ichilov, diagnosis and treatment for Parkinson’s disease patients are provided by Israel’s leading physicians:
Professor Tatyana Gurevich, Head of Movement Disorder and Parkinson’s Disease Division, Professor at Tel Aviv University. One of the best Israeli specialists in the diagnosis and treatment for this condition.
Doctor Amir Dori, famous Israeli neurologist. Specializes in the treatment for peripheral nerve disorders, neuromuscular condition diagnosis, and nerve conduction studies.
Professor Nir Giladi, neurologist, Head of Neurology Department at Ichilov Clinic. Specializes in the diagnosis and therapy for neurological conditions related to movement disorders, walking and balance problems, tremor, seizures, tics and involuntary movements.
Parkinson’s Disease Treatment Methods In Israel
Medications reduce the symptoms of Parkinson’s disease significantly but none of the therapies is able to stop the progression of the disease. Some patients are offered surgery. To others, doctors recommend physical therapy or muscle strengthening. In many cases, the multidisciplinary approach to treatment proves effective.
Therapy for Parkinson’s disease in Israel remains based on levodopa, a drug combined with another medication, carbidopa (Sinemet). Levodopa is quickly converted into dopamine by DOPA decarboxylase enzyme present in the central and peripheral nervous systems. Most of levodopa is metabolized before it enters the brain.
Since these drugs cause side effects and may lose their efficacy after prolonged use, therapy for Parkinson’s disease also includes such medications as dopamine agonists, amantadine, COMT inhibitors and anticholinergic drugs.
If medication therapy proves ineffective, a patient at Top Ichilov Clinic may be offered surgery to alleviate the symptoms and improve the quality of life. Nevertheless, some patients might have contraindications to surgery. For instance, if the patient’s body never responded or stopped responding to levodopa and carbidopa therapy, surgery is unlikely to help them. Indications to surgical intervention are found only in 10% of Parkinson’s disease patients.
The Top Ichilov neurosurgeons use three surgical treatments for Parkinson’s disease:
- Ablative brain surgery. This method helps localize, target and destroy an area of brain affected by Parkinson’s disease. The goal of treatment is to destroy the tissues that generate abnormal chemical or electrical signals causing shaking and other symptoms of Parkinson’s disease. Most patients are recommended a pallidotomy, or a partial destruction of the globus pallidus.Parkinson’s disease treatment center at Ichilov cliinic
- Deep brain stimulation (DBS). Like ablative brain surgery, deep brain stimulation targets shaking and slowed movements characteristic of Parkinson’s disease. During the procedure, a special stimulator is inserted into certain areas of the brain. Instead of destroying overactive cells responsible for the symptoms, DBS temporarily strips them of the ability to send electrical signals. This type of therapy alleviates the symptoms more effectively and causes fewer side effects in comparison with other treatments.
- Transplantation. During transplantation, or reconstructive surgery, the surgeon implants dopamine-producing cells into a certain area of the brain. For these purposes, the doctor may use cells from different sources: from the patient’s own body, from human embryos or from porcine embryos. At present, scientists are verifying whether stem cells may also be used for reconstructive purposes.
How To Receive Diagnosis And Treatment For Parkinson’s Disease In Top Ichilov
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